Sequence-dependent separation of trinucleotides by ion-interaction reversed-phase liquid chromatography—A structure-retention study assisted by soft-modelling and molecular dynamics

Published in Journal of Chromatography A, 2016

Recommended citation: Mikulášek, K., Jaroň, K. S., Kulhánek, P., Bittová, M., & Havliš, J., 2016. "Sequence-dependent separation of trinucleotides by ion-interaction reversed-phase liquid chromatography—A structure-retention study assisted by soft-modelling and molecular dynamics." Journal of Chromatography A, (1469), 88-95. http://doi.org/10.1016/j.chroma.2016.09.060

We showed nearly-deterministic relation of retention times of trinucleotides with their nucleotide composition. We modeled properties of trinucleotide molecules that actually explained most of the variability of the original model. I was invited to this study to construct models.

Paper was published in an evil journal, to get pdf please send me an email.

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